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Mucus is an important difficulty in pulmonary drugs, due to the fact in those with these frequent lung ailments, thick mucus can block the airways and cause indicators starting from a mild cough to quite critical decreases in lung function.
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The compound has the prospective to generally be produced into a sp9 drug to treat mucus accumulation in several frequent lung ailments.
"We built up an image of what the secretory equipment seemed like and we knew all of the big players," Dickey said. "At the time we had an notion of how the many pieces worked together, we decided synaptotagmin-2 (Syt2) was the top protein to focus on to block mucin secretion since it only turns into activated using a large amount of stimulation.
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